ภาวะการแข็งตัวของเลือดในหลอดเลือดแบบแพร่กระจาย (DIC)

Key Facts

• Always secondary to another serious condition (never occurs on its own)
• Common triggers: severe infection/sepsis, cancer, heat stroke, trauma, pancreatitis, snake envenomation
• In cats: lymphoma, hepatic lipidosis, and feline-infectious-peritonitis are common triggers
• Mechanism: widespread inflammation triggers exaggerated clotting, which depletes clotting factors, causing bleeding
• Signs: petechiae (pinpoint bleeding), bruising, bleeding from wounds/IV sites, organ failure
• Diagnosis: coagulation panels, platelet count, D-dimer, antithrombin levels
• Treatment: address underlying cause + fresh frozen plasma + heparin + supportive care
• Prognosis is guarded to poor; early recognition improves outcomes
• Species: dogs (primarily); cats (rare)