มะเร็งเยื่อบุผิวเปลี่ยนผ่าน (TCC)

Key Facts

• Most common bladder tumor in dogs; rare in cats
• Predisposed breeds: Scottish Terrier (18x risk), West Highland White Terrier, Beagle, Shetland Sheepdog
• Signs mimic chronic urinary-tract-infection: bloody urine, straining, frequent urination
• Often located at the bladder trigone, making complete surgical removal difficult
• Diagnosis: ultrasound of bladder, urine cytology, or biopsy (avoid needle aspiration to prevent seeding)
• Treatment: piroxicam (NSAID), mitoxantrone chemotherapy, or combination
• Surgery rarely curative due to location; palliative management common
• Median survival with treatment: 6-12 months
• Species: dogs (primarily)