ภาวะพิษจากยาต้านการอักเสบที่ไม่ใช่สเตียรอยด์ (NSAIDs)

Key Facts

• NSAIDs inhibit cyclooxygenase enzymes, leading to gastrointestinal ulceration, renal failure, and central nervous system depression in pets.
• Cats are particularly sensitive to NSAID toxicity due to deficient glucuronidation pathways in their livers.
• Even small doses of baby aspirin or ibuprofen can cause severe organ damage in dogs and cats.
• Treatment typically involves aggressive intravenous fluid therapy, gastroprotectants, and sometimes dialysis for severe renal compromise.