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Nicotine Toxicity

Poisoning from electronic cigarettes and e-liquid nicotine in pets.

Key Facts

  • Clinical signs at 0.5 mg/kg body weight; 20 mg can be lethal for cats/small dogs
  • E-liquid refill bottles extremely dangerous (up to 1080 mg nicotine in 30 mL bottle)
  • Signs begin within 15-30 minutes: drooling, vomiting, agitation, panting
  • Severe: tremors, seizures, cardiac arrest, coma, death
  • Nicotine absorbed through skin — paw contact with spilled e-juice is dangerous
  • Standard decontamination (inducing vomiting) usually not helpful — too rapid absorption
  • ASPCA Poison Control: 888-426-4435

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