โรคกล้ามเนื้ออ่อนแรงเอ็มจี

Key Facts

• Can be congenital (born with it) or acquired (autoimmune)
• Acquired form most common; often associated with thymoma (thymus tumor)
• Signs: exercise-induced weakness (worse with activity, better with rest), megaesophagus (dilated esophagus), regurgitation
• Focal form may only affect esophagus or facial muscles
• Diagnosis: acetylcholine receptor antibody titer (blood test)
• Treatment: pyridostigmine (anticholinesterase) + immunosuppressive therapy
• Aspiration pneumonia from megaesophagus is the most common life-threatening complication
• Spontaneous remission possible in dogs
• Species: dogs and cats