ภาวะโลหิตจางจากภูมิคุ้มกันทำลายเม็ดเลือดแดง

Key Facts

• Mortality approaches 70% — aggressive treatment essential
• Signs: weakness, yellow/orange tissues (jaundice), dark urine, pale gums
• Spherocytes on blood smear indicate immune-mediated destruction
• Autoagglutination (red cells clumping) is especially foreboding sign
• Thromboembolic disease is main cause of death
• Treatment: immune-suppressive drugs, possible blood transfusions
• Leukemoid reaction: spectacularly high white blood cell counts