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Feline Idiopathic Cystitis
Feline idiopathic cystitis is chronic bladder inflammation with no identifiable bacterial or structural cause. Also called Pandora Syndrome, it is the most common cause of feline-lower-urinary-tract-disease in young cats (~50% of cases). It is a stress-related neurological disorder where sensitive cats have abnormal hormonal stress responses.
Key Facts
- Also called FIC, Pandora Syndrome, feline interstitial cystitis
- Most common urological disease of young cats; uncommon after age 10-12
- Not a bacterial infection; antibiotics are not effective
- Affected cats produce higher catecholamines and lower cortisol in response to stress
- Bladder PSGAG protective lining becomes patchy under stress, exposing tissue to irritating urine
- Episodes typically last 1-2 weeks; no treatment shortens duration
- No definitive diagnostic test; diagnosis by exclusion of stones, infection, tumors
- Male cats at risk for life-threatening urinary-obstruction from mucus/crystal plugs
- Early life stress (orphaned, bottle-fed, trauma) predisposes cats to FIC
- Concurrent issues common: obesity, GI problems, over-grooming, anxiety
- MEMO (Multimodal Environmental Modification) is the evidence-based prevention approach
- Canned urinary formula diets more effective than dry food
- Species: cats
ความเชื่อมโยง (11)
โรคที่เกี่ยวข้อง
Anxietyโรค
Stress triggers and worsens FIC episodes
Bladder Stonesโรค
Must be ruled out; struvite crystals contribute to male cat blockage
Feline Lower Urinary Tract Diseaseโรค
FIC is the #1 cause of FLUTD in young cats
House Soilingโรค
FIC is a leading medical cause of inappropriate elimination
Urinary Obstructionโรค
Life-threatening complication in male cats with FIC
Urinary Tract Infectionโรค
Often confused with UTI but is not an infection