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Clostridium Difficile Infection
A bacterial disease caused by toxin-producing strains of Clostridium difficile that primarily affects the intestines of humans and various animal species.
Key Facts
- The clinical illness is driven by bacterial toxins rather than direct bacterial invasion.
- It is the leading cause of infectious hospital-associated diarrhea in adults in developed countries.
- A hyper-virulent strain known as ribotype 027/NAP1 has triggered severe epidemics across multiple continents.
- Healthy companion animals frequently carry the bacteria asymptomatically, with higher colonization rates in young or hospitalized pets.