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Diagnostic6 connections · 2 sources

Urine Protein Creatinine Ratio

The urine protein:creatinine ratio (UPC) is a test performed on a urine sample to quantify protein loss through the kidneys. It is a key component of chronic-kidney-disease IRIS sub-staging. Excessive protein in the urine indicates damage to the kidney's filtration system (glomerular disease).

Key Facts

  • Sub-staging categories: non-proteinuric, borderline proteinuric, proteinuric
  • Proteinuria indicates glomerular damage (a more severe form of kidney failure)
  • Higher urinary protein loss makes hypertension harder to control long-term
  • pyelonephritis can falsely elevate UPC, leading to incorrect sub-staging
  • Species: dogs and cats

Connections (6)

Related Conditions

Chronic Kidney DiseaseCondition

Part of IRIS sub-staging protocol.

GlomerulonephritisCondition

Key diagnostic and monitoring tool

HypertensionCondition

Higher proteinuria correlates with more difficult blood pressure control.

PyelonephritisCondition

Infection-related protein can skew sub-staging results.

Diagnostics

Blood Pressure MonitoringDiagnostic

UPC and blood pressure are the two sub-staging parameters.

UrinalysisDiagnostic

Sub-staging test performed on the urine sample.

Source Articles (2)

Chronic Kidney Disease In Dogs And Cats Where To BeginHigh Blood Pressure In Our Pets

Backlinks (2)

Cardiac

Urinary

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