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Squamous Cell Carcinoma

Squamous cell carcinoma (SCC) is a malignant tumor arising from squamous epithelial cells. It commonly affects the mouth, nose, and skin in cats and dogs. Oral SCC is particularly aggressive with poor prognosis.

Key Facts

  • Oral SCC: most common oral tumor in cats; locally invasive, rarely metastasizes
  • Nasal SCC in cats: associated with sun exposure; white-faced cats at higher risk
  • Oral SCC in dogs: affects gums, tongue, tonsils; more likely to metastasize than in cats
  • Signs: drooling, difficulty eating, facial swelling, bloody nasal discharge
  • Treatment: surgery when possible; radiation therapy; limited response to chemotherapy
  • Oral SCC in cats has very poor prognosis (median survival 1-3 months)
  • Prevention of nasal SCC: limit sun exposure for light-colored cats
  • Species: dogs and cats

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