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Sepsis

A life-threatening systemic response to infection that causes widespread tissue damage and organ failure.

Key Facts

It occurs when the immune system overreacts to bacteria or toxins from a localized infection.
In uterine disease, it is commonly triggered by advanced pyometra.
Symptoms include extreme lethargy, rapid heart rate, and poor perfusion.
Immediate stabilization, antibiotics, and source removal are required for survival.

Endotoxemia frequently progresses to sepsis as the body's immune response becomes dysregulated.

Pyometra is a primary source of the bacterial infection that triggers sepsis.

Surgical removal of the infected uterus is necessary to eliminate the septic source.